Helper Class for NumericTwoCompartmentExchangeModel: Defines the differential equations (Mass Balance Equations) in the 2 Compartment Exchange model. The 2 Compartment Exchange model is defined via the mass balance equations vp * dCp(t)/dt = F * (CA(t) - Cp(t)) - PS * (Cp(t) - Ce(t)) ve * dCe(t)/dt = PS * (Cp(t) - Ce(t)) Boost ODEINT performs a stepwise numeric integration (e.g. via Runge-Kutta method) of the initial value problem x' = dx/dt = f(x,t) It needs an operator () (a functor) that calculates dx/dt = dxdt for a given x and t. Parameters are F, PS, ve and vp and the time dependent Ca(t) =AIF, that is interpolated to the current step t. More...

#include <mitkTwoCompartmentExchangeModelDifferentialEquations.h>

Public Types
typedef std::vector< double >	AIFType

Public Member Functions
void	operator() (const mitk::NumericTwoCompartmentExchangeModel::state_type &x, mitk::NumericTwoCompartmentExchangeModel::state_type &dxdt, const double t)
	Functor for differential equation of Physiological Pharmacokinetic Brix Model Takes current state x = x(t) and time t and calculates the corresponding dxdt = dx/dt. More...

	TwoCompartmentExchangeModelDifferentialEquations ()

void	initialize (double Fp, double ps, double fi, double fp)
	Initialize class with parameters F/Vp, PS/Vp, fi and fp that are free fit parameters. More...

void	setAIF (AIFType &aif)

void	setAIFTimeGrid (AIFType &grid)

Detailed Description

Helper Class for NumericTwoCompartmentExchangeModel: Defines the differential equations (Mass Balance Equations) in the 2 Compartment Exchange model. The 2 Compartment Exchange model is defined via the mass balance equations vp * dCp(t)/dt = F * (CA(t) - Cp(t)) - PS * (Cp(t) - Ce(t)) ve * dCe(t)/dt = PS * (Cp(t) - Ce(t)) Boost ODEINT performs a stepwise numeric integration (e.g. via Runge-Kutta method) of the initial value problem x' = dx/dt = f(x,t) It needs an operator () (a functor) that calculates dx/dt = dxdt for a given x and t. Parameters are F, PS, ve and vp and the time dependent Ca(t) =AIF, that is interpolated to the current step t.

Definition at line 30 of file mitkTwoCompartmentExchangeModelDifferentialEquations.h.

Member Typedef Documentation

◆ AIFType

typedef std::vector< double > mitk::TwoCompartmentExchangeModelDifferentialEquations::AIFType

Definition at line 34 of file mitkTwoCompartmentExchangeModelDifferentialEquations.h.

Constructor & Destructor Documentation

◆ TwoCompartmentExchangeModelDifferentialEquations()

mitk::TwoCompartmentExchangeModelDifferentialEquations::TwoCompartmentExchangeModelDifferentialEquations ( )

inline

Definition at line 49 of file mitkTwoCompartmentExchangeModelDifferentialEquations.h.

Member Function Documentation

◆ initialize()

void mitk::TwoCompartmentExchangeModelDifferentialEquations::initialize	(	double	Fp,
		double	ps,
		double	fi,
		double	fp
	)

inline

Initialize class with parameters F/Vp, PS/Vp, fi and fp that are free fit parameters.

Definition at line 54 of file mitkTwoCompartmentExchangeModelDifferentialEquations.h.

◆ operator()()

void mitk::TwoCompartmentExchangeModelDifferentialEquations::operator()	(	const mitk::NumericTwoCompartmentExchangeModel::state_type &	x,
		mitk::NumericTwoCompartmentExchangeModel::state_type &	dxdt,
		const double	t
	)

inline

Functor for differential equation of Physiological Pharmacokinetic Brix Model Takes current state x = x(t) and time t and calculates the corresponding dxdt = dx/dt.

Definition at line 39 of file mitkTwoCompartmentExchangeModelDifferentialEquations.h.