Medical Imaging Interaction Toolkit  2018.4.99-86eb38db
Medical Imaging Interaction Toolkit
The Model Fit Inspector View
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Icon of the Model Fit Inspector View

Introduction

This view (Model Fit Inspector; MFI) offers the possibility to display the time course of the signal within an individual voxel (with or without fit).

Contact information

This plug-in is being developed by the SIDT group (Software development for Integrated Diagnostics and Therapy) at the DKFZ (German Cancer Research Center). If you have any questions, need support, find a bug or have a feature request, feel free to contact us at www.mitk.org.

Viewing without a model fit

fit_inspect_raw.png
Example screen shot showing the inspection of raw dynamic data without a fit.
Open the view and select the dynamic image in the data manager. The graph plot will show the time course of image intensities (signal) in the selected voxel (cross hair) as red data points. The blue point indicates the frame currently displayed in the 4-window view.

Viewing without a model fit

fit_inspect_fit.png
Example screen shot showing the inspection of dynamic data and an associated fit.
Selecting a parameter map of the fit of interest in the Data Manager will display the raw data curve in red dots with corresponding fit as black line in the selected cross-hair position. If an AIF-based model was used, the utilized AIF (averaged over AIF mask) is also displayed (default in green). The color of the AIF display can be adjusted. For ROI based fits, the MFI will display both the current data curve in the selected voxel (in red) and the ROI-averaged fitted curve (in dark green, can be adjusted). Scrolling through the individual voxels will change the current data curve, but the ROI-based curve remains the same. If voxels outside the fitted area defined by the mask are selected, the raw data voxel values will be displayed, however no black fit line is visualized.

Below the data plot, several options for data visualization can be selected:

Fit info tab

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Details of the fit info tab.
The Fit info tab displays meta-data for selected fits performed on the displayed data set. If no fit was performed and only raw data is visualized, the fields are empty.

Fit parameter tab

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Details of the fit parameter tab.
The "fit parameter" tab shows fit related parameter estimate values, derived parameters, fit criterion values and (optional) debug parameter maps in the selected voxel (and all inspection positions; see also inspection positions) listed as a table. If no fit was performed and only raw data is visualized, the table is empty. The content of the table may by copied to clipboard or exported as csv file, by clicking the respective button below the table.

Inspection positions tab

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Details of the inspection position tab.
The tab allows to manage inspection positions (see here for more about inspection positions).

  • (1) Shows the coordinates of the current selected position in the workbench.
  • (2) Press to make the current position a inspected position. It will be added at the bottom of the list (3).
  • (3) List of all inspection positions
  • (4) Toggle adding mode on/off. If on, you can add new positions by clicking into render windows with "SHIFT + left mouse button".
  • (5) Manually adding inspection positions by entering the coordinates.
  • (6) Remove the selected inspection positions. (Hot key: Del)
  • (7) Move the selected inspection position up in the list (3).
  • (8) Move the selected inspection position down in the list (3).
  • (9) Save inspection points to a file.
  • (10) Load inspection points from a file.

Settings tab

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Details of the settings tab.
The View settings tab is used to adjust the plot display, namely, x and y axis scales and colors of displayed data plots (i.e. AIF).

Plot data export tab

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Details of the plot data export tab.
Displays voxel data (input image) and corresponding time grid together with model fit values and additional curves (like AIF values) for each time point. The table will contain the position depended values of the current selected position as well as of all inspection positions (see also inspection positions). The data in the table can also be copied to clipboard or exported to csv files, by clicking the respective button below the table.

Inspection positions

fit_inspect_positions_example.png
Example of the usage of inspection positions.
The fit inspector allows to define positions in the world coordinate system that will be constantly displayed in addition to the current selected position. These inspected position will be shown in the following parts of the view:

  • The plot windows. See example image above; the plot shows the current position (raw data: red dots, fit: black line) and an additional inspection position (green).
  • The fit parameter tab (see example image above)
  • The plot data export tab.

It will work with dynamic data with and without an model fit. See the inspection positions tab section for more details on how to manage inspection positions.